Comparing Brand Name Viagra to Generic Sildenafil Citrate

Blocking PDE-5 means increased levels of cGMP within the smooth muscles which promotes muscle relaxation and vasodilation (a widening of blood vessels). High levels of PDE-5 are found in the penis, lungs, and retina. PDE-5 is also found throughout the body within the smooth muscle cells of the blood vessels and muscles. Sildenafil belongs to the drug class called phosphodiesterase (PDE) type 5 inhibitors. Sildenafil (Viagra, Vybrique brands and generic) is used to treat erectile dysfunction (ED, impotence). It increases blood flow to the penis following sexual stimulation by blocking the enzyme responsible for the breakdown of cGMP. This allows men to keep an erection hard enough for sex.

Adverse effects

Animal, Plant, Fish) may require special country importation requirements.USP recommends you contact your country competent authorities to determine if any certifications, permits or licenses may be required prior to ordering.Material Origins are found within the Product under Origin Information. Sildenafil is used to treat erectile dysfunction (ED) in men or pulmonary arterial hypertension (PAH) in both men and women, depending on the brand. Viagra and Vybrique are used for ED and Revatio is used for PAH. Sildenafil works by blocking the action of an enzyme called cGMP-specific phosphodiesterase type-5 (PDE-5). This enzyme breaks down cGMP, a substance that induces smooth muscles to relax. Sildenafil (Viagra, Vybrique brands and generic) only works following sexual stimulation. It works within 30 to 60 minutes, but may be taken up to four hours before sexual activity.

Indication	Patient Group	Dosage Recommendation	Additional Notes
Erectile Dysfunction	Men aged 18-65	50 mg30-1 hour before activity	Adjust based on efficacy and tolerability
Pulmonary Hypertension	Adults with PAH	20 mg three times daily	Extended release available
Raynaud's Phenomenon	People with secondary Raynaud's	Off-label use, consult physician	Limited clinical evidence

Sildenafil (Revatio brand) reduces high blood pressure associated with pulmonary arterial hypertension (PAH). This improves the ability to exercise in people with PAH and delays any worsening of their symptoms. When used to treat PAH, sildenafil is available as tablets (20 mg) for and an IV injection. When used for ED, sildenafil is available as oral tablets of 25 mg, 50 mg, and 100 mg strengths, or an oral film (Vybrique brand) of 25 mg, 50 mg, 75 mg, and 100 mg strengths. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Dyspepsia, flushing, headache, indigestion, muscle or back pain, and visual disturbances are the most common side effects reported.

Product	Dosage	Quantity + Bonus	Price
Viagra Generic	25mg	120 + 6 Pills	125.56€ 119.58€	Buy
Viagra Generic	50mg	30 + 4 Pills	54.26€ 51.68€	Buy
Kamagra Polo	100mg	120 + 6 Pills	327.15€ 311.57€	Buy
Viagra Generic	25mg	360 + 10 Pills	213.68€ 203.50€	Buy
Kamagra	100mg	60 + 4 Pills	201.34€ 191.75€	Buy
Kamagra	100mg	32 Pills	121.24€ 115.47€	Buy
Viagra Generic	150mg	30 + 2 Pills	72.32€ 68.88€	Buy
Viagra Generic	100mg	10 Pills	28.91€ 27.53€	Buy
Viagra Generic	50mg	90 + 6 Pills	107.37€ 102.26€	Buy
Viagra Generic	25mg	30 + 4 Pills	47.97€ 45.69€	Buy
Viagra Generic	50mg	20 Pills	40.52€ 38.59€	Buy
Kamagra Oral Jelly	100mg	110 + 9 Sachets	334.87€ 318.92€	Buy
Kamagra Oral Jelly	100mg	30 + 5 Sachets	136.20€ 129.71€	Buy
Kamagra Polo	100mg	12 Pills	60.21€ 57.34€	Buy
Kamagra Polo	100mg	32 Pills	125.88€ 119.89€	Buy
Viagra Generic	150mg	270 + 10 Pills	326.61€ 311.06€	Buy
Viagra Generic	200mg	90 + 6 Pills	170.79€ 162.66€	Buy

Other side effects include a drop in blood pressure, insomnia, nasal congestion, or a runny nose and nosebleeds. Sudden hearing loss has also been reported. Some people taking sildenafil have had bleeding events; however, it has not been established if this is related to sildenafil use.

• Sildenafil citrate’s patent expiration increased market competition.
• Generics help reduce treatment costs globally.
• Pharmaceutical companies conduct clinical trials regularly.
• Safety monitoring continues post-marketing.
• Adverse event reporting is essential for drug safety.
• Patients should only use approved formulations.
• Counterfeit sildenafil products are a concern.
• Purchase from reputable sources is advised.

Rarely, may decrease blood flow to the optic nerve causing sudden vision loss.

How should this medicine be used?

However, you should never double your dosage. If you completely miss a dose and it’s time for the next dose, skip the one you missed. Are there any safety measures I should take before using this drug? Like most medications, there are precautions you should take sildenafil 200 mg before using this drug. Make sure you talk with your doctor about: any other drugs, medications, herbs, or supplements you take or plan to take any medical conditions or surgeries you have or plan to have if you are pregnant or plan to become pregnant There are other drugs available to treat your condition.

Common Side Effects

Some may be better suited for you than others. Talk with your doctor about other drug options that may work for you. Sildenafil and tadalafil are alike because they both can treat ED and PAH. However, tadalafil has a few distinctions from sildenafil. Tadalafil is the generic name for the erectile dysfunction drug Cialis.

Other warnings

There are two versions of the drug: a version that can be taken as needed Cialis 5-mg daily dosing is the only PDE5 inhibitor dose approved for treating an enlarged prostate; improving ED symptoms is an added benefit of the daily dose. Because of the “as needed” version of tadalafil, some users may find this option more convenient. The downside, however, is that side effects tend to last longer too. The main difference between generic sildenafil and Viagra is marketing. The main ingredient in Viagra is sildenafil, meaning that the drugs are essentially the same. The risk is greater in people aged older than 50, with diabetes, heart disease, high blood pressure, high cholesterol, who smoke, or with certain pre-existing eye problems.

What is Sildenafil and How Does it Work?

When flying, never put it into a checked bag. Keep it in your carry-on bag. Don’t worry about airport X-ray machines. You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled container with you.

Who can use Sildenafil Citrate Tablets?

Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold. If you’re taking this drug for PAH, your doctor may monitor your blood pressure and pulse regularly. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it. Many insurance companies require prior authorization for this drug.

Sildenafil Tablets for ED

This means your doctor may need to get approval from your insurance company before your insurance company will pay for the prescription. Sildenafil under the brand name Viagra is prescribed to treat erectile dysfunction by increasing blood flow to the penis during arousal. Sildenafil under the brand name Revatio is often prescribed to help adults with PAH get more exercise by treating their condition. What if I forget to take it? If you are taking Revatio and you forget to take your scheduled dose, take it as soon as possible. Rarely, may cause other side effects or lead to painful erections lasting longer than four hours.

Society and culture

However, Viagra is marketed and prescribed strictly for erectile dysfunction, while generic sildenafil can be prescribed for PAH as well. Viagra is also known as “the little blue pill” because of its blue color, while generic sildenafil tends to be a white color. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication.

Clinical monitoring

The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. USP Certificates/Product Information Sheets and Valid Use Dates View the USP Certificate or Product Information Sheet in the table above to view additional product details, including available label text and storage information. View the USP Certificate or Product Information Sheet in the table above to view additional product details, including available label text and storage information. 1The Harmonized System (HS) code provided on this webpage is for informational purposes only and is subject to change without notice. See your doctor immediately if this happens. May not be suitable for some people including those with angina, chest pain, other heart conditions, liver or kidney problems, blood or bleeding disorders, stomach ulcers, certain eye conditions, or a physical deformity of the penis (such as Peyronie's disease). Higher dosages of sildenafil are associated with a higher risk of death in children with PAH.

What special dietary instructions should I follow?

The exporter and/or importer of record is responsible for determining the accuracy of items at the time of export/import per U.S. regulations. USP is not sildenafil 60mg responsible for the accuracy or completeness of the information furnished. 2USP procures materials worldwide and most foreign materials do not undergo a fundamental change during the packaging process at USP that would substantially transform the item resulting in a country of origin change from the foreign origin to the United States. Under the Rules of Origin the original foreign country of origin would remain. For this reason, the FDA does not recommend use in children aged less than 18 years. May interact with some medications including certain antibiotics and antifungals, herbal remedies, HIV medicines, nitrates, and drugs used in the treatment of high blood pressure or prostate disorders. Sildenafil should not be taken with other PDE-5 inhibitors. The dosage may need to be reduced in people with kidney or liver disease. More research is needed to establish if sildenafil has a role in sexual dysfunction in women.

• The discovery of sildenafil began with research on heart drugs.
• It was found to cause vasodilation as a side effect.
• Pfizer refined the drug for erectile dysfunction.
• It became a blockbuster drug upon FDA approval.
• Sildenafil has helped millions worldwide.
• It has changed perceptions about male sexual health.
• Ongoing research explores new formulations.
• Awareness campaigns promote safe usage.

Sildenafil offers no protection against sexually transmitted diseases. Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects.

What should I know about storage and disposal of this medication?

How to tell if the drug is working: For ED: You should be able to get and maintain an erection when sexually aroused. For PAH: You should be able to exercise more easily. Your doctor will also check you to determine if this drug is working. Keep these considerations in mind if your doctor prescribes sildenafil for you. You can take this drug with or without food.

Mechanism of Action

You can cut or crush the tablet. When you take the drug depends on the condition being treated:For ED: You can take this drug at any time of day.For PAH: Take this drug three times per day about 4–6 hours apart. Take it at the same time every day. For ED: You can take this drug at any time of day. For PAH: Take this drug three times per day about 4–6 hours apart.

How does sildenafil work (mechanism of action)?

Store sildenafil tablets at room temperature between 59°F and 86°F (15°C and 30°C). Don’t store this medication in moist or damp areas, such as bathrooms. A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.